Assessing patients' risk of febrile neutropenia: is there a correlation between physician-assessed risk and model-predicted risk?

ABSTRACT: This study evaluated the correlation between the risk of febrile neutropenia (FN) estimated by physicians and the risk of severe neutropenia or FN predicted by a validated multivariate model in patients with nonmyeloid malignancies receiving chemotherapy. Before patient enrollment, physician and site characteristics were recorded, and physicians self-reported the FN risk at which they would typically consider granulocyte colony-stimulating factor (G-CSF) primary prophylaxis (FN risk intervention threshold). For each patient, physicians electronically recorded their estimated FN risk, orders for G-CSF primary prophylaxis (yes/no), and patient characteristics for model predictions. Correlations between physician-assessed FN risk and model-predicted risk (primary endpoints) and between physic

SUBMITTER: Lyman GH 

PROVIDER: S-EPMC4559026 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature