Current Developments in Dementia Risk Prediction Modelling: An Updated Systematic Review.

ABSTRACT:

Background

Accurate identification of individuals at high risk of dementia influences clinical care, inclusion criteria for clinical trials and development of preventative strategies. Numerous models have been developed for predicting dementia. To evaluate these models we undertook a systematic review in 2010 and updated this in 2014 due to the increase in research published in this area. Here we include a critique of the variables selected for inclusion and an assessment of model prognostic performance.

Methods

Our previous systematic review was updated with a search from January 2009 to March 2014 in electronic databases (MEDLINE, Embase, Scopus, Web of Science). Articles examining risk of dementia in non-demented individuals and including measures of sensitivity, specific

SUBMITTER: Tang EY 

PROVIDER: S-EPMC4559315 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature