Urinary Bisphenol A Levels during Pregnancy and Risk of Preterm Birth.

ABSTRACT:

Background

Preterm birth (PTB), a leading cause of infant mortality and morbidity, has a complex etiology with a multitude of interacting causes and risk factors. The role of environmental contaminants, particularly bisphenol A (BPA), is understudied with regard to PTB.

Objectives

In the present study we examined the relationship between longitudinally measured BPA exposure during gestation and PTB.

Methods

A nested case-control study was performed from women enrolled in a prospective birth cohort study at Brigham and Women's Hospital in Boston, Massachusetts, during 2006-2008. Urine samples were analyzed for BPA concentrations at a minimum of three time points during pregnancy on 130 cases of PTB and 352 randomly assigned controls. Clinical classifications of PTB wer

SUBMITTER: Cantonwine DE 

PROVIDER: S-EPMC4559950 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature