Magnetic field activated drug delivery using thermodegradable azo-functionalised PEG-coated core-shell mesoporous silica nanoparticles.

ABSTRACT: Core-shell Fe3O4@SiO2 mesoporous silica nanoparticles coated with a new thermodegradable polymer allowed the release of a model drug through heating caused by a high frequency oscillating magnetic field. The thermodegradable polymer was made of poly(ethylene glycol) (PEG) functionalised with azo bonds that break with an elevation of temperature.

SUBMITTER: Saint-Cricq P 

PROVIDER: S-EPMC4560200 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature