Farm Exposure as a Differential Risk Factor in ANCA-Associated Vasculitis.

ABSTRACT: OBJECTIVE:To investigate the association of farm exposure and the development of ANCA-associated vasculitis (AAV). METHODS:One hundred eighty-nine well defined patients with AAV (n = 119 with granulomatosis with polyangiitis [GPA], n = 48 with microscopic polyangiitis [MPA], n = 22 patients with eosinophilic granulomatosis with polyangiitis [EGPA]) and 190 controls (n = 119 patients with rheumatoid arthritis, n = 71 with large vessel vasculitis) were interrogated using a structured questionnaire. Factors investigated were occupation, farm exposure, contact to different livestock, participation in harvesting, residence next to a farm, MRSA status, and contact to domestic pets at disease onset or ever before. The odds ratio (OR) and 95% confidence interval [95%CI] were calculated for each it

SUBMITTER: Willeke P 

PROVIDER: S-EPMC4560371 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature