Diseased Region Detection of Longitudinal Knee Magnetic Resonance Imaging Data.

ABSTRACT: Magnetic resonance imaging (MRI) has become an important imaging technique for quantifying the spatial location and magnitude/direction of longitudinal cartilage morphology changes in patients with osteoarthritis (OA). Although several analytical methods, such as subregion-based analysis, have been developed to refine and improve quantitative cartilage analyses, they can be suboptimal due to two major issues: the lack of spatial correspondence across subjects and time and the spatial heterogeneity of cartilage progression across subjects. The aim of this paper is to present a statistical method for longitudinal cartilage quantification in OA patients, while addressing these two issues. The 3D knee image data is preprocessed to establish spatial correspondence across subjects and/or time. T

SUBMITTER: Huang C 

PROVIDER: S-EPMC4560622 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature