Colorectal Cancer Risk Following Adenoma Removal: A Large Prospective Population-Based Cohort Study.

ABSTRACT:

Background

Randomized controlled trials have demonstrated significant reductions in colorectal cancer incidence and mortality associated with polypectomy. However, little is known about whether polypectomy is effective at reducing colorectal cancer risk in routine clinical practice. The aim of this investigation was to quantify colorectal cancer risk following polypectomy in a large prospective population-based cohort study.

Methods

Patients with incident colorectal polyps between 2000 and 2005 in Northern Ireland were identified via electronic pathology reports received to the Northern Ireland Cancer Registry. Patients were matched to the Northern Ireland Cancer Registry to detect colorectal cancer and deaths up to December 31, 2010. Colorectal cancer standardized incidence

SUBMITTER: Coleman HG 

PROVIDER: S-EPMC4560642 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature