An improved approach to separating startle data from noise.

ABSTRACT:

Background

The acoustic startle reflex (ASR) is a rapid, involuntary movement to sound, found in many species. The ASR can be modulated by external stimuli and internal state, making it a useful tool in many disciplines. ASR data collection and interpretation varies greatly across laboratories making comparisons a challenge.

New method

Here we investigate the animal movement associated with a startle in mouse (CBA/CaJ). Movements were simultaneously captured with high-speed video and a piezoelectric startle plate. We also use simple mathematical extrapolations to convert startle data (force) into center of mass displacement ("height"), which incorporates the animal's mass.

Results

Startle plate force data revealed a stereotype waveform associated with a startle that c

SUBMITTER: Grimsley CA 

PROVIDER: S-EPMC4560645 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature