Population-Based Surveillance of Neisseria meningitidis Antimicrobial Resistance in the United States.

ABSTRACT: Background.  Antimicrobial treatment and chemoprophylaxis of patients and their close contacts is critical to reduce the morbidity and mortality and prevent secondary cases of meningococcal disease. Through the 1990's, the prevalence of antimicrobial resistance to commonly used antimicrobials among Neisseria meningitidis was low in the United States. Susceptibility testing was performed to ascertain whether the proportions of isolates with reduced susceptibility to antimicrobials commonly used for N meningitidis have increased since 2004 in the United States. Methods.  Antimicrobial susceptibility testing was performed by broth microdilution on 466 isolates of N meningitidis collected in 2004, 2008, 2010, and 2011 from an active, population-based surveillance system for susceptibility to c

SUBMITTER: Harcourt BH 

PROVIDER: S-EPMC4561371 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature