Functional neuroanatomical correlates of episodic memory impairment in early phase psychosis.

ABSTRACT: Studies have demonstrated that episodic memory (EM) is often preferentially disrupted in schizophrenia. The neural substrates that mediate EM impairment in this illness are not fully understood. Several functional magnetic resonance imaging (fMRI) studies have employed EM probe tasks to elucidate the neural underpinnings of impairment, though results have been inconsistent. The majority of EM imaging studies have been conducted in chronic forms of schizophrenia with relatively few studies in early phase patients. Early phase schizophrenia studies are important because they may provide information regarding when EM deficits occur and address potential confounds more frequently observed in chronic populations. In this study, we assessed brain activation during the performance of visual scene

SUBMITTER: Francis MM 

PROVIDER: S-EPMC4561590 | biostudies-literature | 2016 Mar

REPOSITORIES: biostudies-literature