Large-scale assessment of olfactory preferences and learning in Drosophila melanogaster: behavioral and genetic components.

ABSTRACT: In the Evolve and Resequence method (E&R), experimental evolution and genomics are combined to investigate evolutionary dynamics and the genotype-phenotype link. As other genomic approaches, this methods requires many replicates with large population sizes, which imposes severe restrictions on the analysis of behavioral phenotypes. Aiming to use E&R for investigating the evolution of behavior in Drosophila, we have developed a simple and effective method to assess spontaneous olfactory preferences and learning in large samples of fruit flies using a T-maze. We tested this procedure on (a) a large wild-caught population and (b) 11 isofemale lines of Drosophila melanogaster. Compared to previous methods, this procedure reduces the environmental noise and allows for the analysis of large popu

SUBMITTER: Versace E 

PROVIDER: S-EPMC4562235 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature