Proteomic approaches for profiling negative fertility markers in inferior boar spermatozoa.

ABSTRACT: The ability to predict male fertility is of paramount importance for animal breeding industries and for human reproduction. Conventional semen analysis generally provides information on the quantitative parameters of spermatozoa, but yields no information concerning its functional competence. Proteomics have identified candidates for male fertility biomarkers, but no studies have clearly identified the relationship between the proteome and sperm fertility. Therefore, we performed a proteomic analysis to investigate small and large litter size boar spermatozoa and identify proteins related to male fertility. In this study, 20 proteins showed differential expression levels in small and large litter size groups. Nineteen of these proteins exhibited decreased expression in large litter size sa

SUBMITTER: Kwon WS 

PROVIDER: S-EPMC4562270 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature