Ontology highlight
ABSTRACT:
SUBMITTER: Luo T
PROVIDER: S-EPMC4562312 | biostudies-literature | 2015 Jan
REPOSITORIES: biostudies-literature
Luo Tianzhi T He Lirong L Theato Patrick P Kiick Kristi L KL
Macromolecular bioscience 20141113 1
Temperature-triggered formation of nanostructures with distinct biological activity offers opportunities in selective modification of matrices and in drug delivery. Toward these ends, diblock polymers comprising poly(diethylene glycol methyl ether methacrylate) (PDEGMEMA) conjugated to a triple helix-forming collagen-like peptide were produced. Triggered by the collapse of the thermoresponsive domain above its LCST, the conjugate undergoes a reversible transition in aqueous solution to form well ...[more]