Likelihood of infection in patients with presumed sepsis at the time of intensive care unit admission: a cohort study.

ABSTRACT:

Introduction

A clinical suspicion of infection is mandatory for diagnosing sepsis in patients with a systemic inflammatory response syndrome. Yet, the accuracy of categorizing critically ill patients presenting to the intensive care unit (ICU) as being infected or not is unknown. We therefore assessed the likelihood of infection in patients who were treated for sepsis upon admission to the ICU, and quantified the association between plausibility of infection and mortality.

Methods

We studied a cohort of critically ill patients admitted with clinically suspected sepsis to two tertiary ICUs in the Netherlands between January 2011 and December 2013. The likelihood of infection was categorized as none, possible, probable or definite by post-hoc assessment. We used multivariable

SUBMITTER: Klein Klouwenberg PM 

PROVIDER: S-EPMC4562354 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature