Inflammatory markers and mortality among US adults with obstructive lung function.

ABSTRACT:

Background and objective

Chronic obstructive pulmonary disease is characterized by an inflammatory state of uncertain significance. The objective of this study was to examine the association between elevated inflammatory marker count (white blood cell count, C-reactive protein and fibrinogen) on all-cause mortality in a national sample of US adults with obstructive lung function (OLF).

Methods

Data for 1144 adults aged 40-79 years in the National Health and Nutrition Examination Survey III Linked Mortality Study were analysed. Participants entered the study from 1988 to 1994, and mortality surveillance was conducted through 2006. White blood cell count and fibrinogen were dichotomized at their medians, and C-reactive protein was divided into >3 and ≤3 g/L. The number of elev

SUBMITTER: Ford ES 

PROVIDER: S-EPMC4562426 | biostudies-literature | 2015 May

REPOSITORIES: biostudies-literature