Adiponectin Gene Polymorphisms are Associated with Increased Risk of Colorectal Cancer.

ABSTRACT:

Background

This meta-analysis investigates the associations of adiponectin (ADIPOQ) genetic polymorphisms with the susceptibility to colorectal cancer (CRC).

Material and methods

2 reviewers independently searched 6 databases - PubMed, Cochrane Library, Ovid, Embase, China National Knowledge Infrastructure (CNKI) and Wanfang databases - to identify published studies relevant to adiponectin gene polymorphisms and CRC. Studies retrieved from database searches were screened using our stringent inclusion and exclusion criteria. Full texts of the selected studies were accessed and related data was extracted using a standardized data extraction form. Comprehensive Meta-analysis 2.0 software was used for statistical analyses.

Results

A total of 188 studies were initially ret

SUBMITTER: Yang X 

PROVIDER: S-EPMC4562615 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature