Risk of leukaemia mortality from exposure to ionising radiation in US nuclear workers: a pooled case-control study.

ABSTRACT:

Objective

To follow-up on earlier studies of the leukaemogenicity of occupational ionising radiation exposure.

Methods

We conducted a nested case-control analysis of leukaemia mortality in a pooled cohort of US nuclear workers followed through 2005. Each case was matched to four controls on attained age. Exposures were estimated from available records. General relative risk models were used to estimate the excess relative risk (ERR) of leukaemia, excluding chronic lymphocytic (CLL), acute myeloid leukaemia, chronic myeloid leukaemia and CLL while controlling for potential confounders. Preferred exposure lags and time-windows of risks were calculated using joint maximum likelihood. Dose-response was also examined using linear, linear-quadratic, categorical and restricted cubi

SUBMITTER: Daniels RD 

PROVIDER: S-EPMC4563861 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature