Enantioselective 1,1-arylborylation of alkenes: merging chiral anion phase transfer with Pd catalysis.

ABSTRACT: A palladium-catalyzed three-component coupling of α-olefins, aryldiazonium salts, and bis(pinacolato)diboron affords direct access to chiral benzylic boronic esters. This process is rendered highly enantioselective using an unprecedented example of cooperative chiral anion phase transfer and transition-metal catalysis.

SUBMITTER: Nelson HM 

PROVIDER: S-EPMC4564013 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature