Association between Perivascular Spaces and Progression of White Matter Hyperintensities in Lacunar Stroke Patients.

ABSTRACT:

Objectives

Perivascular spaces are associated with MRI markers of cerebral small vessel disease, including white matter hyperintensities. Although perivascular spaces are considered to be an early MRI marker of cerebral small vessel disease, it is unknown whether they are associated with further progression of MRI markers, especially white matter hyperintensities. We determined the association between perivascular spaces and progression of white matter hyperintensities after 2-year follow-up in lacunar stroke patients.

Methods

In 118 lacunar stroke patients we obtained brain MRI and 24-hour ambulatory blood pressure measurements at baseline, and a follow-up brain MRI 2 years later. We visually graded perivascular spaces and white matter hyperintensities at baseline. Progress

SUBMITTER: Loos CM 

PROVIDER: S-EPMC4564273 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature