A systematic review and meta-analysis of tobacco use and prostate cancer mortality and incidence in prospective cohort studies.

ABSTRACT:

Context

An association between tobacco smoking and prostate cancer (PCa) incidence and mortality was suggested in an earlier meta-analysis of 24 prospective studies in which dose-response associations and risks per unit of tobacco use were not examined.

Objective

We investigated the association between several measures of tobacco use and PCa mortality (primary outcome) and incidence (secondary outcome) including dose-response association.

Evidence acquisition

Relevant articles from prospective studies were identified by searching the PubMed and Web of Science databases (through January 21, 2014) and reference lists of relevant articles. Combined relative risks (RRs) and 95% confidence intervals (CIs) were calculated using random effects methods. We also calculated pop

SUBMITTER: Islami F 

PROVIDER: S-EPMC4566150 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature