The Spatial Mixing of Genomes in Secondary Contact Zones.

ABSTRACT: Recent genomic studies have highlighted the important role of admixture in shaping genome-wide patterns of diversity. Past admixture leaves a population genomic signature of linkage disequilibrium (LD), reflecting the mixing of parental chromosomes by segregation and recombination. These patterns of LD can be used to infer the timing of admixture, but the results of inference can depend strongly on the assumed demographic model. Here, we introduce a theoretical framework for modeling patterns of LD in a geographic contact zone where two differentiated populations have come into contact and are mixing by diffusive local migration. Assuming that this secondary contact is recent enough that genetic drift can be ignored, we derive expressions for the expected LD and admixture tract lengths acr

SUBMITTER: Sedghifar A 

PROVIDER: S-EPMC4566267 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature