Emergence and predominance of norovirus GII.17 in Huzhou, China, 2014-2015.

ABSTRACT:

Background

Norovirus (NoV) has been recognized as the leading cause of both outbreaks and sporadic cases of acute gastroenteritis in children and adults worldwide. Stool samples collected from outpatients with clinical symptoms of acute gastroenteritis in all age groups at the First People's Hospital in Huzhou, Huzhou, China between March 2014 and February 2015 were analyzed to gain insight into the epidemiology and genetic variation in NoV strains circulating in China.

Method

Real-time RT-PCR (qPCR) was performed for Norovirus detection. RT-PCR were used for genomic amplification and sequencing. Genogroup and genotype were assigned using the NoV Noronet typing tool and the strains were named according to the time of isolation. The phylogenetic analysis was conducted using M

SUBMITTER: Han J 

PROVIDER: S-EPMC4566299 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature