Influence of Thin Slice Reconstruction on CT Brain Perfusion Analysis.

ABSTRACT:

Objectives

Although CT scanners generally allow dynamic acquisition of thin slices (1 mm), thick slice (≥5 mm) reconstruction is commonly used for stroke imaging to reduce data, processing time, and noise level. Thin slice CT perfusion (CTP) reconstruction may suffer less from partial volume effects, and thus yield more accurate quantitative results with increased resolution. Before thin slice protocols are to be introduced clinically, it needs to be ensured that this does not affect overall CTP constancy. We studied the influence of thin slice reconstruction on average perfusion values by comparing it with standard thick slice reconstruction.

Materials and methods

From 50 patient studies, absolute and relative hemisphere averaged estimates of cerebral blood volume (CBV), ce

SUBMITTER: Bennink E 

PROVIDER: S-EPMC4567308 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature