Identification and characterization of β-sitosterol target proteins.

ABSTRACT: β-Sitosterol is the most abundant plant sterol in the human diet. It is also the major component of several traditional medicines, including saw palmetto and devil's claw. Although β-sitosterol is effective against enlarged prostate in human clinical trials and has anti-cancer and anti-inflammatory activities, the mechanisms of action are poorly understood. Here, we report the identification of two new binding proteins for β-sitosterol that may underlie its beneficial effects.

SUBMITTER: Lomenick B 

PROVIDER: S-EPMC4567552 | biostudies-literature | 2015 Nov

REPOSITORIES: biostudies-literature