Collaborative Research in Childhood Cancer Survivorship: The Current Landscape.

ABSTRACT: Survivors of childhood cancer carry a substantial burden of morbidity and are at increased risk for premature death. Furthermore, clear associations exist between specific therapeutic exposures and the risk for a variety of long-term complications. The entire landscape of health issues encountered for decades after successful completion of treatment is currently being explored in various collaborative research settings. These settings include large population-based or multi-institutional cohorts and single-institution studies. The ascertainment of outcomes has depended on self-reporting, linkage to registries, or clinical assessments. Survivorship research in the cooperative group setting, such as the Children's Oncology Group, has leveraged the clinical trials infrastructure to explore th

SUBMITTER: Bhatia S 

PROVIDER: S-EPMC4567704 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature