Airway Obstruction Worsens in Young Adults with Asthma Who Become Obese.

ABSTRACT:

Background

Few studies have examined how developing obesity in early adulthood affects the course of asthma.

Objective

We analyzed lung function and asthma impairment and risk among nonobese children with asthma, comparing those who were obese in young adulthood with those who remained nonobese.

Methods

We carried out the post hoc analysis of 771 subjects with mild to moderate asthma who were not obese (pediatric definition, body mass index [BMI] < 95th percentile) when enrolled in the Childhood Asthma Management Program at ages 5-12 years. The subjects were then followed to age 20 years or more. For visits at ages 20 years or more, spirometry values as percent predicted and recent asthma symptom scores and prednisone exposure were compared between 579 subjects who we

SUBMITTER: Strunk RC 

PROVIDER: S-EPMC4568157 | biostudies-literature | 2015 Sep-Oct

REPOSITORIES: biostudies-literature