Transcriptomic Profiling of Spleen in Grass-Fed and Grain-Fed Angus Cattle.

ABSTRACT: The grass-fed cattle obtain nutrients directly from pastures containing limited assimilable energy but abundant amount of fiber; by contrast, grain-fed steers receive a diet that is comprised mainly of grains and serves as an efficient source of high-digestible energy. Besides energy, these two types of diet differ in a large number of nutritional components. Additionally, animals maintained on rich-energy regimen are more likely to develop metabolic disorders and infectious diseases than pasture raised individuals. Thus, we hypothesize that spleen-a relevant immune organ-may function differently under disparate regimes. The objective of this study was to find the differentially expressed genes in the spleen of grass-fed and grain-fed steers, and furtherly explore the potential involved bi

SUBMITTER: Li Y 

PROVIDER: S-EPMC4569079 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature