The vaginal isolate Lactobacillus paracasei LPC-S01 (DSM 26760) is suitable for oral administration.

ABSTRACT: Bacterial vaginosis is one of the most common urogenital diseases affecting women in reproductive age. The administration of probiotics as vaginal suppository has been proposed as a strategy to cure this condition and reduce its recurrence. Nonetheless, also oral consumption of probiotics, which is a more practical route of administration, proved to be an efficient strategy. In this perspective, we studied Lactobacillus paracasei LPC-S01 (DSM 26760), a human vaginal isolate included in commercial probiotic preparations for topical use, in order to assess if this bacterium can also perform as gastrointestinal probiotic. Comparative genomics revealed the presence of several accessory genes suggesting that LPC-S01 is a niche-generalist member of its species. According to a procedure conventio

SUBMITTER: Balzaretti S 

PROVIDER: S-EPMC4569730 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature