Adiposity and Cardiometabolic Risk in Children With and Without Antipsychotic Drug Treatment.

ABSTRACT:

Context

Pediatric obesity is common, particularly in children treated with antipsychotic medications. Antipsychotic exposure can increase cardiometabolic risk by increasing adiposity, and possibly via other adiposity-independent pathways.

Objective

The objectives were to characterize relationships of adiposity with intrahepatic triglyceride (IHTG) content and carotid intima media thickness (CIMT) in children with and without antipsychotic drug treatment, and to explore whether vitamin D alters any effects in these relationships.

Design

This was a cross-sectional case-control study.

Setting

The setting was an academic medical center.

Patients or other participants

Participants were 44 children (ages, 6-19 y): 25 cases treated with antipsychotic and other

SUBMITTER: Nicol GE 

PROVIDER: S-EPMC4570158 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature