Difference in Association of Obesity With Prostate Cancer Risk Between US African American and Non-Hispanic White Men in the Selenium and Vitamin E Cancer Prevention Trial (SELECT).

ABSTRACT:

Importance

African American men have the highest rates of prostate cancer incidence and mortality in the United States. Understanding underlying reasons for this disparity could identify preventive interventions important to African American men.

Objective

To determine whether the association of obesity with prostate cancer risk differs between African American and non-Hispanic white men and whether obesity modifies the excess risk associated with African American race.

Design, setting, and participants

Prospective study of 3398 African American and 22,673 non-Hispanic white men who participated in the Selenium and Vitamin E Cancer Prevention Trial (2001-2011) with present analyses completed in 2014.

Main outcomes and measures

Total, low-grade (Gleason score <7

SUBMITTER: Barrington WE 

PROVIDER: S-EPMC4570268 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature