The PFP and ESG protein function prediction methods in 2014: effect of database updates and ensemble approaches.

ABSTRACT:

Background

Functional annotation of novel proteins is one of the central problems in bioinformatics. With the ever-increasing development of genome sequencing technologies, more and more sequence information is becoming available to analyze and annotate. To achieve fast and automatic function annotation, many computational (automated) function prediction (AFP) methods have been developed. To objectively evaluate the performance of such methods on a large scale, community-wide assessment experiments have been conducted. The second round of the Critical Assessment of Function Annotation (CAFA) experiment was held in 2013-2014. Evaluation of participating groups was reported in a special interest group meeting at the Intelligent Systems in Molecular Biology (ISMB) conference in Boston

SUBMITTER: Khan IK 

PROVIDER: S-EPMC4570625 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature