Ancient gene duplications have shaped developmental stage-specific expression in Pristionchus pacificus.

ABSTRACT:

Background

The development of multicellular organisms is accompanied by gene expression changes in differentiating cells. Profiling stage-specific expression during development may reveal important insights into gene sets that contributed to the morphological diversity across the animal kingdom.

Results

We sequenced RNA-seq libraries throughout a developmental timecourse of the nematode Pristionchus pacificus. The transcriptomes reflect early larval stages, adult worms including late larvae, and growth-arrested dauer larvae and allowed the identification of developmentally regulated gene clusters. Our data reveals similar trends as previous transcriptome profiling of dauer worms and represents the first expression data for early larvae in P. pacificus. Gene expression cluste

SUBMITTER: Baskaran P 

PROVIDER: S-EPMC4570658 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature