Hypoxaemia as a Mortality Risk Factor in Acute Lower Respiratory Infections in Children in Low and Middle-Income Countries: Systematic Review and Meta-Analysis.

ABSTRACT:

Objective

To evaluate the association between hypoxaemia and mortality from acute lower respiratory infections (ALRI) in children in low- and middle-income countries (LMIC).

Design

Systematic review and meta-analysis.

Study selection

Observational studies reporting on the association between hypoxaemia and death from ALRI in children below five years in LMIC.

Data sources

Medline, Embase, Global Health Library, Lilacs, and Web of Science to February 2015.

Risk of bias assessment

Quality In Prognosis Studies tool with minor adaptations to assess the risk of bias; funnel plots and Egger's test to evaluate publication bias.

Results

Out of 11,627 papers retrieved, 18 studies from 13 countries on 20,224 children met the inclusion criteria. Twelve (66.6

SUBMITTER: Lazzerini M 

PROVIDER: S-EPMC4570717 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature