Lifestyle-Related Factors and Atopy in Seven Danish Population-Based Studies from Different Time Periods.

ABSTRACT:

Background

The prevalence of allergic respiratory disease tends to increase in populations that adopt the so-called Westernized lifestyle. We investigated the association between atopy and several possible lifestyle-related factors in seven Danish population-based studies.

Methods

A total of 20048 persons participated in the seven studies. We used logistic regression to analyse the associations between possible determinants and atopy defined as serum specific IgE or skin prick test positivity against inhalant allergens. Associations were expressed as odds ratios (ORs) with 95% confidence intervals (95% CIs). In addition, individual participant data meta-analyses were performed.

Results

Atopy was significantly associated with younger age (OR per 1 year increase in age:

SUBMITTER: Skaaby T 

PROVIDER: S-EPMC4570778 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature