Temporal Trends and Predictors for Cancer Clinical Trial Availability for Medically Underserved Populations.

ABSTRACT:

Background

Lack of access to available cancer clinical trials has been cited as a key factor limiting trial accrual, particularly among medically underserved populations. We examined the trends and factors in clinical trial availability within a major U.S. safety-net hospital system.

Materials and methods

We identified cancer clinical trials activated at the Harold C. Simmons Cancer from 1991 to 2014 and recorded the characteristics of the trials that were and were not activated at the Parkland Health and Hospital System satellite site. We used univariate and multivariate logistic regression to determine the association between trial characteristics and nonactivation status, and chi-square analysis to determine the association between the trial characteristics and the reason

SUBMITTER: Gerber DE 

PROVIDER: S-EPMC4571795 | biostudies-literature | 2015 Jun

REPOSITORIES: biostudies-literature