Renal formulas pretreated with medications alters the nutrient profile.

ABSTRACT:

Background

Pretreating renal formulas with medications to lower the potassium and phosphorus content is common in clinical practice; however, the effect of this treatment on other nutrients is relatively unstudied. We examine whether nutrient composition is affected by pretreating renal formulas with sodium polystyrene sulfonate (SPS) suspension and sevelamer carbonate.

Methods

Fixed medication doses and treatment times were utilized to determine changes in the nutrient composition of Suplena® and Similac® PM 60/40. The effect of simultaneously adding both medications (co-administration) to the formula on the nutrient composition of Suplena® was also evaluated.

Results

Pretreatment of Suplena® with SPS reduced the concentrations of calcium (11-38 %), copper (3-11 %),

SUBMITTER: Taylor JM 

PROVIDER: S-EPMC4572699 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature