Effect of Grape Polyphenols on Blood Pressure: A Meta-Analysis of Randomized Controlled Trials.

ABSTRACT:

Background

The effect of grape polyphenols on blood pressure remains unclear, which we aimed to address via a meta-analysis study.

Methods

We conducted study trial searches in PubMed, Embase, and the Cochrane Library databases. Summary estimates of weighted mean differences and 95% confidence intervals were obtained by using fixed-effects models. Subgroup analyses were performed to identify the source of heterogeneity. The protocol details of our meta-analysis have been submitted to the international database of prospectively registered systematic reviews (registration number CRD42015019196).

Results

Ten studies were included in the present meta-analysis. Our results showed daily grape polyphenol intake could significantly reduce systolic blood pressure by 1.48 mmHg w

SUBMITTER: Li SH 

PROVIDER: S-EPMC4572713 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature