Lactic acid bacteria: reviewing the potential of a promising delivery live vector for biomedical purposes.

ABSTRACT: Lactic acid bacteria (LAB) have a long history of safe exploitation by humans, being used for centuries in food production and preservation and as probiotic agents to promote human health. Interestingly, some species of these Gram-positive bacteria, which are generally recognized as safe organisms by the US Food and Drug Administration (FDA), are able to survive through the gastrointestinal tract (GIT), being capable to reach and colonize the intestine, where they play an important role. Besides, during the last decades, an important effort has been done for the development of tools to use LAB as microbial cell factories for the production of proteins of interest. Given the need to develop effective strategies for the delivery of prophylactic and therapeutic molecules, LAB have appeared as

SUBMITTER: Cano-Garrido O 

PROVIDER: S-EPMC4573465 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature