Sex differences in the prevalence of diastolic dysfunction in cardiac surgical patients.

ABSTRACT:

Objectives

The mortality from diastolic dysfunction is approximately 9% to 28%. In patients with ischemic heart disease, female sex and advanced age are associated with increases in ventricular diastolic stiffness. Clinical studies have found higher rates of diastolic dysfunction in women, despite higher ejection fractions, than in men post-myocardial infarction. Therefore, we hypothesized that female patients undergoing cardiac surgery have higher degrees of diastolic dysfunction and experience more adverse outcomes, such as prolonged hospitalization.

Methods

We prospectively enrolled 153 patients undergoing cardiac surgery. Diastolic function was assessed using early transmitral velocity (E) and early diastolic lateral mitral annular tissue velocity (e'). Left ventricular

SUBMITTER: Ferreira RG 

PROVIDER: S-EPMC4573536 | biostudies-literature | 2015 Mar

REPOSITORIES: biostudies-literature