Catch Me if You Can: Adaptation from Standing Genetic Variation to a Moving Phenotypic Optimum.

ABSTRACT: Adaptation lies at the heart of Darwinian evolution. Accordingly, numerous studies have tried to provide a formal framework for the description of the adaptive process. Of these, two complementary modeling approaches have emerged: While so-called adaptive-walk models consider adaptation from the successive fixation of de novo mutations only, quantitative genetic models assume that adaptation proceeds exclusively from preexisting standing genetic variation. The latter approach, however, has focused on short-term evolution of population means and variances rather than on the statistical properties of adaptive substitutions. Our aim is to combine these two approaches by describing the ecological and genetic factors that determine the genetic basis of adaptation from standing genetic variation

SUBMITTER: Matuszewski S 

PROVIDER: S-EPMC4574244 | biostudies-literature | 2015 Aug

REPOSITORIES: biostudies-literature