Investigating the Evidence of the Real-Life Impact of Acute Hyperglycaemia.

ABSTRACT:

Unlabelled

Poorly controlled diabetes mellitus (DM) is associated with the development of long-term micro- and macro-vascular complications. The predominant focus of anti-diabetic therapy has been on lowering glycosylated haemoglobin levels, with a strong emphasis on fasting plasma glucose (particularly in Type 2 DM). There is considerable evidence indicating that post-meal hyperglycaemic levels are independently associated with higher risks of macro-vascular disease. Although some have identified mechanisms which may account for these observations, interventions which have specifically targeted postprandial glucose rises showed little or no effect in reducing cardiovascular risk. Clinical experience and some recent studies suggest acute hyperglycaemia affects cognition and other i

SUBMITTER: Heller S 

PROVIDER: S-EPMC4575298 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature