Near-Infrared Fluorescence Lymphatic Imaging in Lymphangiomatosis.

ABSTRACT:

Background

Lymphangiomatosis is a rare disorder of the lymphatic system that can impact the dermis, soft tissue, bone, and viscera and can be characterized by lymphangiomas, swelling, and chylous discharge. Whether disordered lymphangiogenesis in lymphangiomatosis affects the function and anatomy of the entire systemic lymphatic circulation or is localized to specific sites is not fully known.

Methods and results

A 35-year-old Caucasian female diagnosed with whole-body lymphangiomatosis at 2 months of age and who continues to present with progressive disease was imaged with near-infrared fluorescence lymphatic imaging. While the peripheral lymphatics in the extremities appeared largely normal compared to prior studies, we observed tortuous lymphatic vessels, fluorescence dra

SUBMITTER: Rasmussen JC 

PROVIDER: S-EPMC4575506 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature