Nutritional screening is strongly associated with overall survival in patients treated with targeted agents for metastatic renal cell carcinoma.

ABSTRACT:

Background

Although commonly observed, malnutrition is poorly characterized and frequently underdiagnosed in patients with metastatic renal cell carcinoma (RCC). The ability of nutritional screening tools to predict overall survival (OS) in patients with RCC has not been adequately validated. The objective of this study was to investigate the performance of nutritional screening tools and their additional prognostic value in patients with metastatic RCC treated with targeted therapies.

Methods

Patients were prospectively recruited from three tertiary hospitals between 2009 and 2013. Nutritional status was evaluated using the Geriatric Nutritional Risk Index (GNRI) and the Mini Nutritional Assessment-Short Form (MNA-SF). Their OS and early grade 3/4 adverse events were record

SUBMITTER: Gu W 

PROVIDER: S-EPMC4575553 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature