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Successful Treatment of Carbapenemase-Producing Pandrug-Resistant Klebsiella pneumoniae Bacteremia.


ABSTRACT: New antibiotic options are urgently needed for the treatment of carbapenem-resistant Enterobacteriaceae infections. We report a 64-year-old female with prolonged hospitalization following an intestinal transplant who developed refractory bacteremia due to a serine carbapenemase-producing pandrug-resistant isolate of Klebsiella pneumoniae. After failing multiple antimicrobial regimens, the patient was successfully treated.

SUBMITTER: Camargo JF 

PROVIDER: S-EPMC4576028 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature

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Successful Treatment of Carbapenemase-Producing Pandrug-Resistant Klebsiella pneumoniae Bacteremia.

Camargo Jose F JF   Simkins Jacques J   Beduschi Thiago T   Tekin Akin A   Aragon Laura L   Pérez-Cardona Armando A   Prado Clara E CE   Morris Michele I MI   Abbo Lilian M LM   Cantón Rafael R  

Antimicrobial agents and chemotherapy 20151001 10


New antibiotic options are urgently needed for the treatment of carbapenem-resistant Enterobacteriaceae infections. We report a 64-year-old female with prolonged hospitalization following an intestinal transplant who developed refractory bacteremia due to a serine carbapenemase-producing pandrug-resistant isolate of Klebsiella pneumoniae. After failing multiple antimicrobial regimens, the patient was successfully treated. ...[more]

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