Gastrostomy in patients with amyotrophic lateral sclerosis (ProGas): a prospective cohort study.

ABSTRACT:

Background

Gastrostomy feeding is commonly used to support patients with amyotrophic lateral sclerosis who develop severe dysphagia. Although recommended by both the American Academy of Neurology and the European Federation of Neurological Societies, currently little evidence indicates the optimum method and timing for gastrostomy insertion. We aimed to compare gastrostomy insertion approaches in terms of safety and clinical outcomes.

Methods

In this large, longitudinal, prospective cohort study (ProGas), we enrolled patients with a diagnosis of definite, probable, laboratory supported, or possible amyotrophic lateral sclerosis who had agreed with their treating clinicians to undergo gastrostomy at 24 motor neuron disease care centres or clinics in the UK. The primary outcom

SUBMITTER: ProGas Study Group 

PROVIDER: S-EPMC4578147 | biostudies-literature | 2015 Jul

REPOSITORIES: biostudies-literature