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Design and synthesis of fused polycycles via Diels-Alder reaction and ring-rearrangement metathesis as key steps.

ABSTRACT: Atom efficient processes such as the Diels-Alder reaction (DA) and the ring-rearrangement metathesis (RRM) have been used to design new polycycles. In this regard, ruthenium alkylidene catalysts are effective in realizing the RRM of bis-norbornene derivatives prepared by DA reaction and Grignard addition. Here, fused polycycles are assembled which are difficult to produce by conventional synthetic routes.

SUBMITTER: Kotha S

PROVIDER: S-EPMC4578369 | biostudies-literature | 2015

REPOSITORIES: biostudies-literature

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Design and synthesis of fused polycycles via Diels-Alder reaction and ring-rearrangement metathesis as key steps.

Kotha Sambasivarao S Ravikumar Ongolu O

Beilstein journal of organic chemistry 20150727

Atom efficient processes such as the Diels-Alder reaction (DA) and the ring-rearrangement metathesis (RRM) have been used to design new polycycles. In this regard, ruthenium alkylidene catalysts are effective in realizing the RRM of bis-norbornene derivatives prepared by DA reaction and Grignard addition. Here, fused polycycles are assembled which are difficult to produce by conventional synthetic routes. ...[more]

PMID: 26425184

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