Oxidized Low-Density Lipoprotein and the Incidence of Proliferative Diabetic Retinopathy and Clinically Significant Macular Edema Determined From Fundus Photographs.

ABSTRACT:

Importance

Studies have shown oxidized low-density lipoprotein to be associated with the incidence of proliferative retinopathy and other complications of type 1 diabetes mellitus. Because low-risk interventions are available to modify oxidized low-density lipoprotein, it is important to examine the relationships between this factor and the incidence of proliferative retinopathy and of macular edema, 2 important causes of visual impairment in people with type 1 diabetes.

Objective

To determine the association of oxidized low-density lipoprotein with the worsening of diabetic retinopathy and the incidence of proliferative retinopathy and of macular edema.

Design, setting, and participants

Of 996 participants with type 1 diabetes in the Wisconsin Epidemiologic Study of

SUBMITTER: Klein R 

PROVIDER: S-EPMC4578718 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature