Children's perceptions about medicines: individual differences and taste.

ABSTRACT:

Background

Bitter taste receptors are genetically diverse, so children likely vary in sensitivity to the "bad" taste of some pediatric formulations. Based on prior results that variation in a bitter taste receptor gene, TAS2R38, was related to solid (pill) formulation usage, we investigated whether this variation related to liquid formulation usage and young children's reports of past experiences with medicines and whether maternal reports of these past experiences were concordant with those of their children.

Methods

We conducted retrospective interviews of 172 children 3 to 10 years old and their mothers (N = 130) separately in a clinical research setting about issues related to medication usage. Children were genotyped for the TASR38 variant A49P (alanine to proline at po

SUBMITTER: Mennella JA 

PROVIDER: S-EPMC4578784 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature