Microvascular and Macrovascular Abnormalities and Cognitive and Physical Function in Older Adults: Cardiovascular Health Study.

ABSTRACT:

Objectives

To evaluate and compare the associations between microvascular and macrovascular abnormalities and cognitive and physical function

Design

Cross-sectional analysis of the Cardiovascular Health Study (1998-1999).

Setting

Community.

Participants

Individuals with available data on three or more of five microvascular abnormalities (brain, retina, kidney) and three or more of six macrovascular abnormalities (brain, carotid artery, heart, peripheral artery) (N = 2,452; mean age 79.5).

Measurements

Standardized composite scores derived from three cognitive tests (Modified Mini-Mental State Examination, Digit-Symbol Substitution Test, Trail-Making Test (TMT)) and three physical tests (gait speed, grip strength, 5-time sit to stand)

Results

Parti

SUBMITTER: Kim DH 

PROVIDER: S-EPMC4578971 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature