Intestinal microbial communities associated with acute enteric infections and disease recovery.

ABSTRACT:

Background

The intestinal microbiome represents a complex network of microbes that are important for human health and preventing pathogen invasion. Studies that examine differences in intestinal microbial communities across individuals with and without enteric infections are useful for identifying microbes that support or impede intestinal health.

Results

16S rRNA gene sequencing was conducted on stool DNA from patients with enteric infections (n = 200) and 75 healthy family members to identify differences in intestinal community composition. Stools from 13 patients were also examined post-infection to better understand how intestinal communities recover. Patient communities had lower species richness, evenness, and diversity versus uninfected communities, while principle co

SUBMITTER: Singh P 

PROVIDER: S-EPMC4579588 | biostudies-literature | 2015 Sep

REPOSITORIES: biostudies-literature